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Why Weight Gain Happens Despite Taking Semaglutide Weight gain on semaglutide occurs through five primary mechanisms: inadequate dosing relative to your metabolic needs, compensatory overeating triggered by reduced medication tolerance, increased insulin sensitivity leading to fat storage, water retention from medication side effects, and rebound metabolic adaptation when appetite suppression plateaus

(2023, January 4)

Heartburn: Increased acidity or reflux can occur when the digestive system slows down more than usual

To get the best results, its essential to follow the guidelines for storage, handling, and administration