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Proc Natl Acad Sci U S A 89: 8641-8645, 1992

The campaign targets 1624-year-olds after data revealed: An eight-fold increase in people seeking treatment for ketamine use since 2015 5,448 drug poisoning deaths in England and Wales in 2023 - the highest since records began The initiative warns that recreational drug use can cause irreparable bladder damage, poisoning, and even death, with particular risks from synthetic opioids hidden in fake medicines and THC vapes containing synthetic cannabinoids like spice

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Anesthesia was initiated intramuscularly (4.4 mg/kg telazol and 2.2 mg/kg xylazine) and subsequently maintained with an inhaled halogenated anesthetic (isoflurane, 0.75-3.0%)