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The continuation group
After injection, withdraw the needle in the same direction it entered, and release the pinched skin gently
The decision depends on factors such as: Starting BMI Weight-loss history Type 2 diabetes or insulin resistance Surgical and anaesthetic risk Medication tolerance Patient preference Long-term treatment goals NICE also emphasises that bariatric surgery assessment should involve a multidisciplinary team with medical, nutritional, psychological and surgical expertise
Common adverse effects , particularly during dose titration, include: Gastrointestinal symptoms: nausea (12-22% of patients), diarrhoea, vomiting, constipation, and abdominal discomfort Decreased appetite, which contributes to weight loss but may be troublesome for some patients Injection site reactions (usually mild) Fatigue (less common than gastrointestinal effects) Gastrointestinal adverse effects are typically most pronounced during the first 4-8 weeks and often improve with continued treatment
