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Scientific Mechanism: The Tri-Agonist Effect Retatrutide (LY3437943) is a single peptide molecule that exhibits agonist activity at the Glucagon-Like Peptide-1 (GLP-1), Glucose-Dependent Insulinotropic Polypeptide (GIP), and Glucagon (GCG) receptors

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A one-compartment linear model with linear absorption was used to describe VPA concentrationtime profiles after oral exposure, as defined by the following equation: where C (t) is plasma VPA concentration