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The best results seem to come with doses around 2,000 mg per day among overweight and obese individuals, and the effects typically appear over 12 to 24 weeks , with weight loss plateauing after a few months in most studies

In some embodiments, the chronic inflammation is secondary to obesity, Type 1 Diabetes (T1), Type 2 Diabetes (T2D), metabolic syndrome, chronic kidney disease or cardiovascular disease