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10.3390/nu11071606 211

6 Conclusion and outlook Depression is a prevalent mental disorder characterized by persistent symptoms such as low mood and reduced interest, with severe cases sometimes leading to suicidal tendencies, and has been a major contributor to poor global health and disability, with a recently increasing incidence (ZHANG X

LR3IGF-I is better able to stimulate the type I IGF receptor and thus induce a higher level of activation of intracellular signalling molecules which are responsible for promoting cell survival by inhibition of apoptosis

However, the condition is most commonly found in patients with obesity, diabetes, and possibly obstructive sleep apnea