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However, science is particularly interested in it because of its many physiological, endocrine and modulatory effects, such as its ability to alter corticotropin levels, inhibit somatostatin secretion, normalize blood pressure, reduce stress, influence sleep rhythms, or chronic pain perception

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Dubnov S, Bennett ER, Yayon N, Yakov O, Bennett DA, Seshadri S, Mufson E, Tzur Y, Greenberg D, Kuro-o M, Paldor I, Abraham CR, Soreq H (2024) Knockout of the longevity gene Klotho perturbs aging and Alzheimers disease-linked brain microRNAs and tRNA fragments

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