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in 2019 and confirmed to be true for a low C/D ratio in a study 2 years later (161163)

Gut colonization with methanogenic archaea reduced plasma TMAO levels and attenuated the burden of AS, with decreased area and fat content in the atherosclerotic plaques, in Apo E / mice fed a TMA-supplemented or high choline diet (Ramezani et al., 2018)

Estrogen treatment inhibits lipoperoxides and caspase 3 and 8 associated with oxidative stress and apoptosis in aged keratinocytes (Tresguerres et al., 2008)