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Rybelsus and Trulicity are both FDA-approved GLP-1 receptor agonists that help regulate blood sugar levels in patients with type 2 diabetes, but they differ significantly in administration: Rybelsus is the first oral semaglutide (taken as a daily pill), while Trulicity (dulaglutide) requires a weekly injection

Diabetes Care (2009) 32(Suppl 2):S23745.10.2337/dc09-S355 158 ReeveJRJrEysseleinVERosenquistGZeehJRegnerUHoFJet alEvidence that CCK-58 has structure that influences its biological activity