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So, we dont know if supplementing with glutathione would consistently result in increased glutathione levels or whether such an increase would be clinically significant

Of relevance, recent evidence indicates that SAM exerts anti-inflammatory effects by reducing the expression of the proinflammatory cytokine tumor necrosis factor-alpha (TNF) and increasing the expression of the anti-inflammatory cytokine interleukin 10 (IL-10)

Electrical stimulation therapies such as TENS and PEMF also reduce pain

Understanding these options allows researchers to select the approach best suited to their specific goals and circumstances