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Furthermore, BPC-157 has been observed to stimulate the messenger RNA (mRNA) of early growth response 1 (EGR-1) and its repressor, nerve growth factor 1-A binding protein-2 (NAB2), in intestinal cells

Conclusion In summary, we successfully incorporated two cell-targeting motifs into tripeptide-1 (GHK), a well-known cosmetic peptide, resulting in the development of two chimeric peptides, namely, RGD-GHK and sOtx2-GHK

Important caveat: the human evidence base is thin and largely unreplicated outside the original Russian groups, and most data are preclinical or older clinical work without modern independent confirmation [13]

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