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As the image below shows, fat consumption has steadily risen over the last century since we discovered how to extract oil from crops at scale, fuelled by synthetic fertilisers

While the inherent pharmacokinetic properties of each GLP-1 receptor agonist largely determine elimination time, several patient-specific factors can influence how quickly or slowly these medications clear from the body

Many also find it easier to stick with lifestyle changes, making their transformations sustainable

Obstetrics & Gynecology study followed 234 women with PCOS on semaglutide and found 65% recovered ovulation as measured by mid-luteal progesterone within 6 months