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Approximately 42% of American adults lack adequate insurance coverage for weight loss medications, yet effective GLP-1 compounds remain accessible through direct-pay models

Furthermore, the SELECT trial showed a 20% reduction in major adverse cardiovascular event risk in patients with obesity and without diabetes who lost weight with semaglutide treatment 10

The company holds 114 publications across 14 patent families that are directly relevant to GCGR/GIPR/GLP-1R tri-agonism, weighted almost entirely toward method-of-use claims

Storage and stability after reconstitution Reconstituted retatrutide is a protein in solution, and like all proteins in solution, it degrades over time