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Indole, indoxyl-3-sulfate, indole-3-propionic acid and indole-3-aldehyde can activate AhR signaling in astrocytes, thus suppressing neuroinflammation

(60(10)):1335-1348 doi:10.1007/s40262-021-01025-x

Survodutide represents a mechanistic evolution that addresses a key limitation of GLP-1 monotherapy by adding glucagon-mediated energy expenditure and direct hepatic fat reduction