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Crucially, this glucose-dependent mechanism means insulin is only released when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia compared with some other diabetes medications

This large-scale analysis suggests that OSA status may act as an effect modifier in the association between GLP-1-RA prescription and mortality. The results of this study may lead to OSA diagnosis identifying diabetes patients more likely to derive mortality benefit from GLP-1 therapythe 20% greater relative mortality reduction in patients with OSA supports considering OSA status when making GLP-1 prescribing decisions, the investigators say

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