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While broad-spectrum inhibitors such as azole antifungals have demonstrated efficacy, they are limited by off-target effects and drugdrug interactions

Its broad spectrum of biological activity has drawn significant interest within the scientific and medical communities, particularly regarding its potential use in the treatment of injuries, chronic disorders, and inflammatory conditions

The CYP11A1 enzyme then cuts cholesterol to make pregnenolone

Correlates of protection can be identified by studying immunity in protected and unprotected individuals during natural infection studies but can also be inferred from postvaccination protection