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The central dogma of glucose uptake by pancreatic -cells was that the responsible transporter was GLUT2

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Metabolome reflects the ongoing (patho)physiological state of the body or of a cell/tissue, and provides valuable insights into the biochemical processes underlying a disease that potentially could be used as targets for drug development 22,23

The observed activity level was consistent with the predicted value of 500 U L 1, confirming the reliability and validity of the RSM analysis under the specified experimental conditions