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Neither method significantly improved intracellular (whole-blood) glutathione levels, suggesting a need for alternative strategies or precursors for optimal efficacy

Additionally, patients receiving tirzepatide demonstrated significantly higher serum levels of luteinizing hormone, follicle-stimulating hormone, sex hormone-binding globulin, total, free, and bioavailable testosterone, and significantly lower levels of estradiol than those in the lifestyle changes-only and testosterone therapy groups

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