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Recent studies have shed light on the therapeutic potential of liraglutide and Ex-4 for demyelinating disorders, mainly MS ( The aim of this review is to characterize GLP-1RAs as favorable factors for myelin formation and maintenance and discuss the possibilities of their repositioning for peripheral nerve injury and demyelinating disorders
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In this study, an automated high-throughput approach was employed for a systemic amino acid scanning of semaglutides backbone to enhance GLP-1R ECD affinity and GLP-1R activation thereafter
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