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The one-month results on semaglutide vary widely, but by week 12 most people have established a clear downward trend on the scale

We are also recommending that if patients are starting these drugs or increasing the dose of these drugs, they should do so slowly to reduce the risk of dropping their blood sugar and causing an osmotic shift. Bradley Katz, MD, PhD We as well as other concerned physicians are also asking FDA to mandate a post-marketing survey of these drugs to find the true incidence of eye complications associated with them

Another study on the effect of dulaglutide on stroke showed that dulaglutide reduced the incidence of stroke in middle-aged and elderly people with T2MD and other cardiovascular risk factors, but it cannot reduce the severity of stroke (88)

These may include nausea, decreased appetite, vomiting, constipation, diarrhea, bloating, or abdominal discomfort