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Epigenetic processessuch as DNA methylation and histone modification further contribute to thermal memory, facilitating faster activation of heat-response genes upon recurrent stress exposure

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However, free radicals generated as a result of metabolic events can accumulate in the body and lead to the deterioration of the egg or sperm

514 Targeting translation and epigenetic regulation Transcriptional and translational studies have provided a scientific foundation for the discovery of drug targets for underlying mechanisms, such as PI3K/mTOR pathways