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Arrestin2 and arrestin3 follow the same regulatory pathway It has been reported that both arrestin2 and arrestin3 are deubiquitinated and form stable complexes with G in response to D 3 R desensitization [35], indicating that both of these isoforms are likely implicated in D 3 R desensitization

Carlberg I, Mannervik B

Given as a single agent, it promotes modest increases in survival, and these effects are enhanced when combined with oxaliplatin and/or irinotecan (FOLFOX, FOLFIRI) 2,3