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Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13 , 30753087

Additionally, the prevalence of depression and anxiety was found to be 42.2 and 52.5%, respectively (327)

This phenomenon may stem from the presence of mono-, di-, and tri-phosphorylated forms of the protein

The PIONEER 8 trial [192] (ClinicalTrials.gov identifier: NCT03021187) was a 52-week, double-blind trial in patients with type 2 diabetes uncontrolled on insulin with or without metformin were assigned to once-daily oral semaglutide 3 mg, semaglutide 7 mg, semaglutide 14 mg or to placebo